Joshua Dubland

Research Classification

Research Interests

Newborn Screening
Biochemical Genetics
Lipids
Metabolism
mass spectrometry

Affiliations to Research Centres, Institutes & Clusters

Research Options

I am available and interested in collaborations (e.g. clusters, grants).
I am interested in and conduct interdisciplinary research.
I am interested in working with undergraduate students on research projects.

Biography

Dr. Joshua Dubland is a laboratory scientist and clinical assistant professor in the Department of Pathology and Laboratory Medicine at BC Children's Hospital, 亚洲天堂. Dr. Dubland completed his BSc in chemistry at Simon Fraser University, followed by an MSc in organic chemistry at the University of Toronto. He was then a research associate in the pharmaceutical industry for 4 years, working at both BRI Biopharmaceutical Research Inc. and QLT Inc. Work in the pharmaceutical industry focused on bioanalytical mass spectrometry development, validation, and data acquisition to support clinical and preclinical drug trials. Following this, Dr. Dubland completed his PhD in Experimental Medicine at 亚洲天堂 where his research focused on cellular mechanisms of lipid accumulation and removal in atherosclerosis. Dr. Dubland is currently located in the Newborn Screening and Biochemical Genetics Laboratory at BC Children's Hospital where his current research interests focus on the development of novel mass spectrometry-based assays for clinical diagnosis of inborn errors of metabolism. Additional research interests include applications of mass spectrometry and other next generation analytical technologies for biomarker and drug target discovery. Investigation of inherited lipid metabolism disorders, lysosomal storage disorders, and environmental stress factors associated with lifetime cardiovascular disease risk are of particular interest.

Research Methodology

Mass Spectrometry, metabolomics, lipidomics
Clinical assay development and implementation

Publications

  • (2022)
    Trends in Cardiovascular Medicine,
  • (2022)
    Journal of Mass Spectrometry and Advances in the Clinical Lab, 23, 7--13
  • (2021)
    Journal of mass spectrometry and advances in the clinical lab,
  • (2021)
    Pediatric nephrology (Berlin, Germany),
  • (2021)
    Arteriosclerosis, Thrombosis, and Vascular Biology, 41 (6)
  • (2019)
    Current opinion in lipidology,
  • (2019)
    Arteriosclerosis, thrombosis, and vascular biology,
  • (2018)
    Arteriosclerosis, thrombosis, and vascular biology,
  • (2017)
    Annals of hepatology,
  • (2017)
    Clinical journal of the American Society of Nephrology : CJASN,
  • (2016)
    Current opinion in lipidology,
  • (2015)
    Frontiers in cell and developmental biology,
  • (2012)
    Journal of Clinical Pathology,
  • (2011)
    Tetrahedron,
  • (2009)
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry,

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