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Prospective Graduate Students / Postdocs
This faculty member is currently not actively recruiting graduate students or Postdoctoral Fellows, but might consider co-supervision together with another faculty member.
Sriram Subramaniam
Professor
Research Classification
Research Interests
Structural Biology
cryo-electron microscopy
drug discovery
Cryo-electron tomography
Antibody design
drug discovery
Protein therapeutics
COVID-19 therapeutic design
Infectious disease
Artificial Intelligence
Machine Learning
Relevant Thesis-Based Degree Programs
Affiliations to Research Centres, Institutes & Clusters
Research Options
I am interested in and conduct interdisciplinary research.
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Research Methodology
electron microscopes operating at cryogenic temperatures
News Releases
This list shows a selection of news releases by ÑÇÖÞÌìÌà Media Relations over the last 5 years.
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(17 Sep 2020)
Publications
- (2024)
Current Opinion in Cell Biology, 86 - (2024)
Nature Communications, 15 (1) - (2024)
Nature Structural and Molecular Biology, 31 (3), 424-435 - (2024)
IUCrJ, 11 (Pt 2), 140-151 - (2024)
Transplantation, 108 (4), E49-E62 - (2024)
Nature Methods, 21 (1), 18-19 - (2023)
Structure, 31 (7), 790-800.e4 - (2023)
Proceedings of the National Academy of Sciences of the United States of America, 120 (37) - (2023)
Biophysical Reviews, 15 (1), 89-91 - (2023)
Cell Reports, 42 (1) - (2022)
Nature Methods, 19 (1), 20-23 - (2022)
IUCrJ, 9, 98-103 - (2022)
IUCrJ, 9 (6), 713-714 - (2022)
Encyclopedia of Cell Biology: Volume 1-6, Second Edition, 2, 51-60 - (2022)
Chemical Reviews, 122 (17), 13881-13882 - (2022)
iScience, 25 (8) - (2022)
Science, 375 (6582), 760-764 - (2022)
Nature Communications, 13 (1) - (2022)
Nature Communications, 13 (1) - (2022)
Nature Chemical Biology, 18 (9), 963-971 - (2022)
Chemical Reviews, 122 (17), 14066-14084 - (2021)
eLife, 10 - (2021)
Journal of Biological Chemistry, 297 (4) - (2021)
PLoS Biology, 19 (4) - (2021)
Scientific Reports, 11 (1) - (2021)
eLife, 10, 1-24 - (2021)
Current Opinion in Structural Biology, 71, 223-231 - (2021)
Cell Reports, 37 (12) - (2020)
IUCrJ, 7, 639-643 - (2020)
Journal of Biological Chemistry, 295 (4), 1105-1119 - (2020)
IUCrJ, 7, 575-576 - (2020)
Microscopy and Microanalysis - (2020)
Microscopy and Microanalysis - (2020)
Cell, 183 (2), 429-441.e16 - (2020)
Proceedings of the National Academy of Sciences of the United States of America, 117 (14), 8032-8043 - (2020)
IUCrJ, 7, 453-461 - (2020)
Cancer Cell, 38 (6), 753-756 - (2019)
Cell Reports, 27 (2), 387-399.e7 - (2019)
MRS Bulletin, 44 (12), 929-934 - (2019)
Science, 366 (6461), 109-115 - (2019)
Nature Structural and Molecular Biology, 26 (8), 679-685 - (2019)
IEEE Transactions on Visualization and Computer Graphics, 25 (2), 1378-1391 - (2019)
Annual Review of Biomedical Engineering, 21, 395-415 - (2019)
Journal of Structural Biology, 207 (1), 1-11 - (2019)
Nucleic Acids Research, 47 (17), 9400-9409 - (2018)
Structure, 26 (6), 848-856.e3 - (2018)
Nature, 558 (7711), 553-558 - (2018)
Nature, 561 (7724), E44 - (2018)
Cell Reports, 23 (9), 2832 - (2018)
Current Opinion in Microbiology, 43, 199-207 - (2018)
eLife, 7 - (2018)
Science, 359 (6373), 339-343 - (2017)
Nature Microbiology, 2 (10), 1415-1424 - (2017)
Cell, 171 (2), 414-426.e12 - (2017)
Current Opinion in Structural Biology, 46, 71-78 - (2017)
eLife, 6 - (2017)
Cell Reports, 19 (3), 487-496 - (2016)
Science, 351 (6275), 871-875 - (2016)
Cell, 165 (7), 1698-1707 - (2016)
mBio, 7 (2) - (2016)
Molecular Pharmacology, 90 (1), 35-41 - (2016)
Proceedings of the National Academy of Sciences of the United States of America, 113 (32), 8903-8905 - (2016)
Cell, 164 (4), 747-756 - (2016)
IUCrJ, 3, 3-7 - (2016)
Encyclopedia of Cell Biology, 2, 44-50 - (2016)
Journal of Virology, 90 (17), 7618-7627 - (2016)
Current Opinion in Structural Biology, 41, 194-202 - (2016)
Scientific Reports, 6 - (2016)
Nature, 537 (7621), 567-571 - (2016)
Nucleic Acids Research, 44 (7), 3420-3431 - (2016)
Nature Methods, 13 (8), 607-608 - (2016)
Molecular Pharmacology, 89 (6), 645-651 - (2015)
Science, 348 (6239), 1147-1151 - (2015)
Nature Communications, 6 - (2015)
Nature Communications, 6 - (2015)
Nature Methods, 12 (11), 1021-1031 - (2015)
Retrovirology, 12 (1) - (2015)
Nature Communications, 6 - (2015)
Nature, 523 (7562), 617-620 - (2014)
Nature Structural and Molecular Biology, 21 (10), 841-845 - (2014)
Microscopy and Microanalysis, 20 (3), 774-775 - (2014)
Journal of Structural Biology, 185 (3), 278-284 - (2014)
Scientific Reports, 4 - (2014)
Advances in Imaging and Electron Physics, 185, 113-137 - (2014)
Journal of Virology, 88 (18), 10958-10962 - (2014)
Nature, 514 (7522), 328-334 - (2014)
Proceedings of the National Academy of Sciences of the United States of America, 111 (32), 11709-11714 - (2014)
Journal of Virology, 88 (18), 10327-10339 - (2014)
Annual Review of Virology, 1 (1), 453-473 - (2013)
Journal of Structural Biology, 181 (2), 116-127 - (2013)
Trends in Microbiology, 21 (8), 397-404 - (2013)
PLoS ONE, 8 (11) - (2013)
FEBS Journal, 280 (1), 28-45 - (2013)
PLoS ONE, 8 (11) - (2013)
Proceedings of the National Academy of Sciences of the United States of America, 110 (15), 5921-5926 - (2013)
Current Opinion in Structural Biology, 23 (2), 268-276 - (2013)
Journal of Virology, 87 (12), 7191-7196 - (2013)
Proceedings of the National Academy of Sciences of the United States of America, 110 (2), 513-518 - (2013)
Nature Structural and Molecular Biology, 20 (12), 1352-1357 - (2013)
Proceedings of the National Academy of Sciences of the United States of America, 110 (12), 4592-4597 - (2013)
Proceedings of the National Academy of Sciences of the United States of America, 110 (45) - (2013)
Journal of Structural Biology, 183 (3), 429-440 - (2012)
Journal of Structural Biology, 178 (2), 98-107 - (2012)
Journal of Structural Biology, 178 (2), 165-176 - (2012)
Nature Structural and Molecular Biology, 19 (12), 1203-1207 - (2012)
Structure, 20 (12), 2003-2013 - (2012)
IEEE Transactions on Medical Imaging, 31 (12), 2241-2252 - (2012)
PLoS Pathogens, 8 (7), 37 - (2012)
Resonance, 17 (12), 1157-1164 - (2012)
IEEE Computer Graphics and Applications, 32 (5), 39-49 - (2011)
Molecular Microbiology, 79 (3), 677-685 - (2011)
Analytical Chemistry, 83 (4), 1207-1213 - (2011)
Journal of Structural Biology, 176 (3), 268-278 - (2011)
Journal of Visualized Experiments (58) - (2011)
Blood, 118 (18), 4841-4852 - (2011)
EMBO Journal, 30 (9), 1719-1729 - (2011)
Journal of Bacteriology, 193 (6), 1341-1350 - (2011)
Proceedings of the National Academy of Sciences of the United States of America, 108 (24), 9798-9803 - (2011)
Journal of Virology, 85 (23), 12114-12123 - (2011)
Proceedings of the National Academy of Sciences of the United States of America, 108 (28), 11440-11445 - (2010)
Proceedings of the National Academy of Sciences of the United States of America, 107 (30), 13336-13341 - (2010)
FEMS Microbiology Letters, 313 (2), 89-95 - (2010)
Journal of Structural Biology, 171 (2), 125-132 - (2010)
PLoS Pathogens, 6 (12) - (2009)
Journal of Structural Biology, 166 (3), 316-328 - (2009)
Journal of Structural Biology, 166 (1), 1-7 - (2009)
Pattern Recognition, 42 (6), 1067-1079 - (2009)
Nature Reviews Microbiology, 7 (9), 666-675 - (2009)
PLoS Pathogens, 5 (9) - (2009)
Current Opinion in Structural Biology, 19 (4), 402-407 - (2009)
PLoS ONE, 4 (6) - (2009)
PLoS ONE, 4 (7) - (2009)
Current Opinion in Structural Biology, 19 (4), 433-439 - (2008)
Microscopy and Microanalysis, 14 (SUPPL. 2), 972-973 - (2008)
Journal of Bacteriology, 190 (20), 6805-6810 - (2008)
Journal of Structural Biology, 162 (3), 436-450 - (2008)
Nanomedicine, 3 (1), 125-131 - (2008)
Journal of Structural Biology, 164 (1), 7-17 - (2008)
Structure, 16 (1), 93-103 - Molecular Architecture of Native HIV-1 gp 120 Trimers (2008)
Chemtracts, 21 (6), 227-228 - (2008)
Nature, 455 (7209), 109-113 - (2008)
Proceedings of the National Academy of Sciences of the United States of America, 105 (43), 16555-16560 - (2008)
Molecular and Cellular Proteomics, 7 (2), 442-447 - (2008)
Journal of Bacteriology, 190 (7), 2588-2596 - (2007)
Journal of Structural Biology, 158 (3), 318-326 - (2007)
Journal of Bacteriology, 189 (20), 7503-7506 - (2007)
2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings, 244-247 - (2007)
Journal of Biological Chemistry, 282 (38), 27754-27759 - (2007)
2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings, 233-235 - (2007)
Proceedings of the National Academy of Sciences of the United States of America, 104 (10), 3777-3781 - (2007)
Methods in Cell Biology, 2007 (79), 373-384 - (2007)
PLoS Pathogens, 3 (5), 0571-0581 - (2007)
Current Opinion in Structural Biology, 17 (5), 596-602 - (2007)
2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings, 304-307 - (2007)
ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings, 1 - (2007)
2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings, 217-220 - (2006)
Microscopy and Microanalysis, 12 (SUPPL. 2), 1100-1101 - (2006)
Microscopy and Microanalysis, 12 (SUPPL. 2), 526-527 - (2006)
2nd ASM-IEEE EMBS Conference on Bio-, Micro- and Nanosystems, 37 - (2006)
Journal of Biological Chemistry, 281 (7), 4364-4370 - (2006)
Journal of Structural Biology, 155 (1), 63-73 - (2006)
Microscopy and Microanalysis, 12 (SUPPL. 2), 26-27 - (2006)
PLoS Pathogens, 2 (8), 0727-0730 - (2005)
IEEE Transactions on Image Processing, 14 (9), 1314-1323 - (2005)
Current Opinion in Microbiology, 8 (3), 316-322 - (2005)
Journal of Structural Biology, 150 (2), 144-153 - A new approach for 3D segmentation of cellular tomograms obtained using three-dimensional electron microscopy (2004)
2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, 1, 5-8 - A template-propagation method for segmentation of filamentous structures in electron tomograms (2004)
2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, 1, 1-4 - (2004)
Journal of Microscopy, 216 (1), 76-83 - (2004)
Microscopy and Microanalysis, 10 (SUPPL. 2), 1124-1125 - (2004)
Biophysical Journal, 87 (5), 3600-3607 - (2004)
Journal of Bacteriology, 186 (15), 5052-5061 - (2004)
Annual Review of Biophysics and Biomolecular Structure, 33, 141-155 - (2003)
Microscopy and Microanalysis, 9 (SUPPL. 2), 1168-1169 - (2003)
Journal of Structural Biology, 141 (1), 63-76 - (2003)
Journal of Structural Biology, 143 (2), 135-144 - (2003)
Journal of Bacteriology, 185 (12), 3636-3643 - (2003)
Journal of Structural Biology, 144 (3), 320-326 - (2003)
FEBS Letters, 545 (1), 2-8 - (2003)
Journal of Bacteriology, 185 (5), 1712-1718 - (2002)
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 360 (1794), 859-874 - (2002)
EMBO Journal, 21 (21), 5587-5598 - (2002)
Microscopy and Microanalysis, 8 (SUPPL. 2), 214-215 - (2002)
Journal of Molecular Biology, 319 (2), 555-565 - (2002)
Nature Structural Biology, 9 (8), 597-600 - (2001)
Journal of Structural Biology, 135 (3), 251-261 - (2001)
EMBO Journal, 20 (16), 4408-4413 - (2000)
Quarterly Reviews of Biophysics, 33 (1), 1-27 - (2000)
Biochimica et Biophysica Acta - Bioenergetics, 1460 (1), 157-165 - (2000)
Molecular Membrane Biology, 17 (3), 165-174 - (1999)
Ultramicroscopy, 75 (4), 235-250 - (1999)
Journal of Structural Biology, 128 (1), 19-25 - (1999)
Journal of Molecular Biology, 287 (1), 145-161 - (1999)
Current Opinion in Structural Biology, 9 (4), 462-468 - (1997)
Proceedings of the National Academy of Sciences of the United States of America, 94 (5), 1767-1772 - Evidence for a long-lived 13-cis-containing intermediate in the photocycle of the Leu 93 → Ala bacteriorhodopsin mutant (1997)
Journal of Physical Chemistry B, 101 (29) - (1997)
Journal of Physical Chemistry B, 101 (29), 5619-5621 - (1997)
Journal of Bioenergetics and Biomembranes, 29 (1), 55-59 - (1997)
Proceedings of the National Academy of Sciences of the United States of America, 94 (10), 4966-4971 - (1997)
Proceedings of the National Academy of Sciences of the United States of America, 94 (10), 5028-5033 - Structural changes underlying proton pumping by Bacteriorhodopsin (1997)
FASEB Journal, 11 (9) - (1997)
Biochemistry, 36 (8), 2188-2196 - (1996)
Biochemistry, 35 (6), 1848-1855 - (1996)
Biophysical Journal, 70 (5), 2366-2372 - (1995)
Proceedings of the National Academy of Sciences of the United States of America, 92 (24), 11120-11124 - (1994)
Science, 266 (5189), 1369-1373 - Electron diffraction analysis of structural changes in the photocycle of bacteriorhodopsin (1993)
EMBO Journal, 12 (1), 1-8 - Hydrophobic amino acids in the retinal-binding pocket of bacteriorhodopsin (1993)
Journal of Biological Chemistry, 268 (27), 20305-20311 - Aspartic acid 85 in bacteriorhodopsin functions both as proton acceptor and negative counterion to the schiff base (1992)
Journal of Biological Chemistry, 267 (36), 25730-25733 - Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin (1992)
Journal of Biological Chemistry, 267 (36), 25734-25738 - (1991)
Proceedings of the National Academy of Sciences of the United States of America, 88 (15), 6873-6877 - (1991)
Proceedings of the National Academy of Sciences of the United States of America, 88 (6), 2583-2587 - (1990)
Proceedings of the National Academy of Sciences of the United States of America, 87 (3), 1013-1017 - Ultraviolet-visible transient spectroscopy of bacteriorhodopsin mutants: Evidence for two forms of tyrosine-185 → phenylalanine (1990)
Journal of Biological Chemistry, 265 (28), 16978-16984 - (1989)
Proceedings of the National Academy of Sciences of the United States of America, 86 (2), 529-533 - (1987)
Journal of Physical Chemistry, 91 (7), 1715-1718 - (1985)
Journal of Physical Chemistry, 89 (17), 3592-3595 - (1985)
Science, 227 (4685), 415-417
Proceedings of the National Academy of Sciences of the United States of America, 83
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