Mads Daugaard

Prospective Graduate Students / Postdocs

This faculty member is currently not looking for graduate students or Postdoctoral Fellows. Please do not contact the faculty member with any such requests.

Associate Professor

Research Interests

Cancer Diagnosis and Detection
Cancer biology
Cancer diagnostics
Cancer therapy
Cell Signaling and Cancer
Cell Therapy of Cancer
Chemotherapy
DNA damage response pathways
glycobiology
Immunotherapy
Radiotherapy
Cell stress and Cancer
Cell stress signalling in cancer

Relevant Thesis-Based Degree Programs

Affiliations to Research Centres, Institutes & Clusters

Research Options

I am available and interested in collaborations (e.g. clusters, grants).
I am interested in and conduct interdisciplinary research.

Biography

Dr. Mads Daugaard is Head of the Molecular Pathology and Cell Imaging Unit, Senior Research Scientist at Vancouver Prostate Centre (VPC), and associate Professor at Department of Urologic Sciences, University of British Columbia (亚洲天堂). Daugaard operates in the translational cancer research space, integrating basic cancer discovery research with experimental therapeutic and diagnostic development in high-risk adult and childhood solid tumors. As part of his translational research focus, Daugaard has established the therapeutic development companies VAR2 Pharmaceuticals and OncoMal (2012), and the cancer diagnostics company VARCT Diagnostics (2017) to facilitate translation of his research towards the clinical arena. He is a co-PI of the VPC small-molecule drug development pipeline ADDUCT. Daugaard has attracted > $10M in federal and foundation support for his academic research programs and secured investments of >$10M for commercial development and translation of his research discoveries. He received the 2019 Robert J. Arceci Innovation Award from the St. Baldrick鈥檚 Foundation in 2019 and the Prostate Cancer Canada Rising Star Award in 2014.

Research Methodology

Recombinant proteins
biochemistry
molecular biology
Flow cytometry
Mass Spectrometry
CRISPR/Cas9 technology
Mouse models of cancer
Cancer cell line panels
bioinformatics
DNA and RNA Sequencing
Molecular pathology
Translational oncology

Publications

  • (2022)
    Scientific reports,
  • (2021)
    Cells,
  • (2021)
    Science advances,
  • (2021)
    Cell death & disease,
  • (2021)
    Oncogene,
  • (2021)
    Blood Cancer Discovery, 2 (6), 648--665
  • (2021)
    Cancers,
  • (2021)
    Cancer discovery,
  • (2020)
    Cell Death Discovery,
  • (2020)
    Glycobiology,
  • (2020)
    Molecular cell,
  • (2020)
    Cell death & disease,
  • (2020)
    Cancer research,
  • (2020)
    Nature medicine,
  • (2020)
    Cells,
  • (2020)
    Urologic Oncology: Seminars and Original Investigations, 38 (12), 858--866
  • (2020)
    Medical Devices and Sensors, n/a (n/a), e10146
  • (2019)
    eLife,
  • (2019)
    Genome medicine,
  • (2019)
    Cells,
  • (2019)
    APL bioengineering,
  • (2019)
    The American journal of surgical pathology,
  • (2019)
    The American journal of surgical pathology,
  • (2019)
    Transfusion medicine reviews,
  • (2018)
    Oncotarget,
  • (2018)
    Cell Death & Disease,
  • (2018)
    Molecular cancer therapeutics,
  • (2018)
    EMBO molecular medicine,
  • (2018)
    Nature communications,
  • (2017)
    European urology,
  • (2017)
    Cancer,
  • (2017)
    International journal of cancer,
  • DRES-10. THE DISTINCT CYTOTOXIC MECHANISM OF DIANHYDROGALACTITOL (VAL-083) OVERCOMES CHEMORESISTANCE AND PROVIDES NEW OPPORTUNITIES FOR COMBINATION THERAPY IN THE TREATMENT OF GLIOBLASTOMA. (2017)
    Neuro-Oncology,
  • (2017)
    BMJ open,
  • (2017)
    Nature Communications,
  • (2017)
    Developmental dynamics : an official publication of the American Association of Anatomists,
  • (2017)
    Neuro-oncology,
  • (2017)
    Scientific reports,
  • (2017)
    Neuro-oncology,
  • PDTM-27. DIANHYDROGALACTITOL (VAL-083) OVERCOMES CHEMORESISTANCE IN PEDIATRIC MALIGNANT BRAIN TUMORS AND DISPLAYS SYNERGY WITH TOPOISOMERASE INHIBITORS. (2017)
    Neuro-Oncology,
  • (2016)
    Nucleic acids research,
  • (2016)
    Molecular cancer research : MCR,
  • (2016)
    Neuro-oncology,
  • (2016)
    PLoS Pathogens,
  • (2016)
    Sensing and Bio-Sensing Research,
  • (2016)
    Molecular cancer therapeutics,
  • (2016)
    Cell reports,
  • (2015)
    Blood,
  • (2015)
    Oncogene,
  • (2015)
    Cancer cell,
  • (2014)
    Proceedings of the National Academy of Sciences of the United States of America,
  • (2013)
    Nature communications,
  • (2013)
    Oncogene,
  • (2012)
    Molecular cell,
  • (2012)
    Oncogene,
  • (2012)
    Nature structural & molecular biology,
  • (2011)
    The Journal of biological chemistry,
  • (2010)
    Molecular cancer therapeutics,
  • (2007)
    Cancer research,
  • (2007)
    FEBS letters,
  • (2005)
    Cell cycle (Georgetown, Tex.),
  • (2005)
    Genes & development,

Current Students & Alumni

This is a small sample of students and/or alumni that have been supervised by this researcher. It is not meant as a comprehensive list.

Membership Status

Partner appointment
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Location

Vancouver General Hospital

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